Found by the merchant Dejen in Arcadia, this weapon has a lot of potential if you got the right build. One of the many great features in Fallout 4 is the ability to modify your weapons. As an added bonus, the mod also includes a can opener you can use as a melee weapon. 25 Best Fallout 4 Weapon Mods To Dominate The Wasteland. I personally would pick my Grognak's axe or irradiated sledgehammer (+50 base radiation damage). Melee weapons will ignore some of the foe's defense, more for every weapon skill level. For Fallout 4 on the PlayStation 4, a GameFAQs message board topic titled 'best melee weapon?' Some of them are unique, others are added to leveled lists. I'm currently playing a melee character (no sneak build, just full frontal attacks) and I've been wondering what you guys think is the best melee weapon out there. Fallout New Vegas has many melee weapons, and it also has a vast array of unique melee weapons that have a unique appearance or a special effect. This list focuses on the best melee weapons in the Fallout 4. Literally, it's one of the absolute weakest.